12T Velos FTICR-MS

12T Velos FTICR-MS

The Velos FT-12T is the 2nd generation of 12T Trap-FTMS systems constructed in the center.  This instrument was constructed in 2010 and serves to accelerate Top Down proteomics research.

Related Publications

  • Tran JC, Zamdborg L, Ahlf DR, Lee JE, Catherman AD, Durbin KR, Tipton JD, Vellaichamy A, Kellie JF, Li M, Wu C, Sweet SM, Early BP, Siuti N, LeDuc RD, Compton PD, Thomas PM, Kelleher NL "Mapping intact protein isoforms in discovery mode using top-down proteomics." Nature, 2011, 480(7376) p. 254-8.
    Summary | Full Text (PMC) | Full Text (DOI)

  • Kellie JF, Catherman AD, Durbin KR, Tran JC, Tipton JD, Norris JL, Witkowski CE 2nd, Thomas PM, Kelleher NL "Robust analysis of the yeast proteome under 50 kDa by molecular-mass-based fractionation and top-down mass spectrometry." Anal Chem, 2012, 84(1) p. 209-15.
    Summary | Full Text (PMC) | Full Text (DOI)

  • Vellaichamy A, Tran JC, Catherman AD, Lee JE, Kellie JF, Sweet SM, Zamdborg L, Thomas PM, Ahlf DR, Durbin KR, Valaskovic GA, Kelleher NL "Size-sorting combined with improved nanocapillary liquid chromatography-mass spectrometry for identification of intact proteins up to 80 kDa." Anal Chem, 2010, 82(4) p. 1234-44.
    Summary | Full Text (PMC) | Full Text (DOI)

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